Synthesis of mesoionic triazoline nucleosides
- 1 January 1990
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 12,p. 3243-3247
- https://doi.org/10.1039/p19900003243
Abstract
A new type of protected mesoionic triazoline nucleoside was synthesized by the reaction of protected 1,2-dideoxy-hydrazino-D-ribose or 1-deoxy-hydrazino-D-ribose with isothiouronium compounds. The three compounds obtained 10a, 10f and 16a were deprotected with tetrabutylammonium fluoride. They showed no activity against HSV-1 virus.Keywords
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