A new method for the oxidation of alkenes to enones. An efficient synthesis of Δ5-7-oxo steroids
- 1 January 1985
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 2,p. 267-273
- https://doi.org/10.1039/p19850000267
Abstract
A variety of cycloalkenes were converted into α,β-unsaturated ketones using t-butyl hydroperoxide in the presence of chromium hexacarbonyl catalyst. The scope of the reaction has been partly investigated, and it was found that the allylic oxidation proceeds selectively in the presence of some secondary alcohols. High-yield conversions of steroidal 5,6-enes into the corresponding 5,6-en-7-ones are reported.This publication has 2 references indexed in Scilit:
- Organoiron complexes in organic synthesis. Part 19. Trichothecene analogs. Total synthesis of 12,13-epoxy-14-methoxytrichothecene via organoiron complexesJournal of the American Chemical Society, 1981
- The synthesis of chiral subunits for macrolide synthesis: the Prelog-Djerassi lactone and derivativesThe Journal of Organic Chemistry, 1981