Renal secretion of xenobiotics mediated by P-glycoprotein: Importance to renal function in health and exploitation for targeted drug delivery to epithelial cysts in polycystic kidney disease
- 1 May 1997
- journal article
- review article
- Published by Elsevier in Advanced Drug Delivery Reviews
- Vol. 25 (2-3) , 243-256
- https://doi.org/10.1016/s0169-409x(97)00502-4
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- Renal secretion of organic cations: a multistep processAdvanced Drug Delivery Reviews, 1997
- Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.Journal of Clinical Investigation, 1995
- Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugsPublished by Elsevier ,1994
- Transepithelial secretion, cellular accumulation and cytotoxicity of vinblastine in defined MDCK cell strainsBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1993
- BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTERAnnual Review of Biochemistry, 1993
- Quantitative expression patterns of multidrug‐resistance P‐glycoprotein (MDR1) and differentially spliced cystic‐fibrosis transmembrane‐conductance regulator mRNA transcripts in human epitheliaEuropean Journal of Biochemistry, 1992
- Transepithelial vinblastine secretion mediated by P-glycoprotein is inhibited by forskolin derivativesBiochemical and Biophysical Research Communications, 1991
- Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.Journal of Histochemistry & Cytochemistry, 1990
- Identification of P-glycoprotein in renal brush border membranesBiochemical and Biophysical Research Communications, 1989
- Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein.Journal of Histochemistry & Cytochemistry, 1989