Measurement of the arterial concentration of Gd‐DTPA using MRI: A step toward quantitative perfusion imaging
- 1 August 1996
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 36 (2) , 225-231
- https://doi.org/10.1002/mrm.1910360209
Abstract
A noninvasive method using an inversion recovery turbo-FLASH for dynamic measurement of the arterial input function represented by the bolus passage of Gd-DTPA in the descending aorta is presented, and the results are compared with the input function obtained by arterial blood samples. A good accordance between the two input functions was found, indicating that it is possible to measure the input function to the myocardium using MRI. A variation between the two concentration curves of 5% at upslope, 2.7% at peak point, and <7% at downslope was found. The study also indicates that a short inversion time <250 ms has to be used to ensure correct measurement of peak concentration.Keywords
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