The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants
- 1 November 1989
- journal article
- Published by Springer Nature in Nature
- Vol. 342 (6248) , 396-401
- https://doi.org/10.1038/342396a0
Abstract
The requirement for DNA sequence homology in generalized genetic recombination is greatly relaxed in bacterial mutL, mutS and mutH mutants deficient in mismatch repair. In such mutants, intergeneric recombination occurs efficiently between Escherichia coli and Salmonella typhimurium, which are approximately 20% divergent in DNA sequence. This finding has implications for speciation, for regulating recombination between diverged repeated sequences, and for hitherto difficult interspecies hybridizations.Keywords
This publication has 51 references indexed in Scilit:
- Mismatch repair and the fidelity of genetic recombinationGenome, 1989
- Mismatch repair and recombination in E. coliCell, 1987
- Mismatch-stimulated killing.Proceedings of the National Academy of Sciences, 1986
- Involvement of Escherichia coli Mismatch Repair in DNA Replication and RecombinationPublished by Cold Spring Harbor Laboratory ,1984
- Lower fidelity of RecA protein catalysed homologous pairing with a superhelical substrateNature, 1982
- Procedure for production of hybrid genes and proteins and its use in assessing significance of amino acid differences in homologous tryptophan synthetase alpha polypeptides.Proceedings of the National Academy of Sciences, 1981
- Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction.Proceedings of the National Academy of Sciences, 1980
- ON THE MECHANISM OF DEOXYRIBONUCLEATE INTEGRATION IN PNEUMOCOCCAL TRANSFORMATIONProceedings of the National Academy of Sciences, 1964
- A mechanism for gene conversion in fungiGenetics Research, 1964
- A Theory of Crossing-Over by Means of Hybrid Deoxyribonucleic AcidNature, 1963