Crocacin, a new electron transport inhibitor from Chondromyces cracatus (myxobacteria). Production, isolation, physico-chemical and biological properties.
- 1 January 1994
- journal article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 47 (8) , 881-886
- https://doi.org/10.7164/antibiotics.47.881
Abstract
Crocacin was isolated from the biomass of the myxobacterium Chondromyces crocatus, strain Cm c3. It inhibited the growth of a few Gram-positive bacteria and a wide spectrum of yeasts and molds. In beef heart submitochondrial particles, crocacin blocked the electron transport within the bc1-segment (complex III) and caused a red shift in the reduced spectrum of cytochrome b with a maximum at 569 nm.Keywords
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