Characterization of a Bacillus subtilis Thermosensitive Teichoic Acid-Deficient Mutant: Gene mnaA ( yvyH ) Encodes the UDP- N -Acetylglucosamine 2-Epimerase
Open Access
- 1 August 2002
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 184 (15) , 4316-4320
- https://doi.org/10.1128/jb.184.15.4316-4320.2002
Abstract
The Bacillus subtilis thermosensitive mutant ts-21 bears two C-G→T-A transitions in the mnaA gene. At the nonpermissive temperature it is characterized by coccoid cell morphology and reduced cell wall phosphate content. MnaA converts UDP- N -acetylglucosamine into UDP- N -acetylmannosamine, a precursor of the teichoic acid linkage unit.Keywords
This publication has 24 references indexed in Scilit:
- Bacterial polysaccharide synthesis and gene nomenclatureTrends in Microbiology, 1996
- Enzymatic Formation and Release of a Stable Glycal Intermediate: The Mechanism of the Reaction Catalyzed by UDP-N-Acetylglucosamine 2-EpimeraseJournal of the American Chemical Society, 1996
- The tagGH operon of Bacillus subtilis 168 encodes a two‐component ABC transporter involved in the metabolism of two wall teichoic acidsMolecular Microbiology, 1995
- Sequence analysis of the 308 to 311 segment of the Bacillus subtilis 168 chromosome, a region devoted to cell wall metabolism, containing non-coding grey holes which reveal chromosomal rearrangementsMicrobiology, 1995
- Sequencing and analysis of the divergon comprising gtaB, the structural gene of UDP-glucose pyrophosphorylase of Bacillus subtilis 168Journal of General Microbiology, 1993
- Compositional Analysis of Peptidoglycan by High-Performance Anion-Exchange ChromatographyAnalytical Biochemistry, 1993
- A conditional-lethal mutant of Bacillus subtilis 168 with a thermosensitive glycerol-3-phosphate cytidylyltransferase, an enzyme specific for the synthesis of the major wall teichoic acidJournal of General Microbiology, 1991
- Mutants of Bacillus subtilis 168 Thermosensitive for Growth and Wall Teichoic Acid SynthesisMicrobiology, 1989
- The essential nature of teichoic acids in Bacillus subtilis as revealed by insertional mutagenesisMolecular Genetics and Genomics, 1989
- Linkage Units in Cell Walls of Gram-Positive BacteriaCritical Reviews in Microbiology, 1989