Jejunal lysozyme activity and the Paneth cell in coeliac disease.
Open Access
- 1 January 1979
- Vol. 20 (1) , 55-58
- https://doi.org/10.1136/gut.20.1.55
Abstract
The jejunal mucosa of patients with coeliac disease contains significantly fewer Paneth cells (PCC) per crypt (p less than 0.001) and tissue lysozyme activity (JLA) P less than 0.001) when compared with a group of subjects with normal jejunal mucosa. Neither PCC nor JLA return to normal with complete clinical recovery and otherwise complete histological recovery on a gluten free diet. There is a significant linear correlation between JLA and PCC suggesting that the Paneth cell is the principal source of jejunal lysozyme.This publication has 13 references indexed in Scilit:
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