Biosynthesis of vitamin B12: proof of A-B structure for sirohydrochlorin by its specific incorporation into cobyrinic acid
- 1 January 1978
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 3,p. 150-151
- https://doi.org/10.1039/c39780000150
Abstract
Of the two alternative structures we previously derived for sirohydrochlorin, the preferred one (3) is now established by specific incorporation of methyl-labelled sirohydrochlorin into cobyrinic acid (6) followed by degradation to determine the labelling pattern.This publication has 1 reference indexed in Scilit:
- Biosynthesis of porphyrins and related macrocycles. Part 10. Vitamin B12: biochemical derivation of cobyrinic acid from uroporphyrinogen III, studies with the corresponding ring c methyl hepta-carboxylic porphyrinogen, and proof of seven intact methyl transfersJournal of the Chemical Society, Perkin Transactions 1, 1977