Nearly Total Absence of Pulmonary Perfusion with Corresponding Technetium-99m MDP and Gallium-67 Uptake in a Patient with Mediastinal Neuroblastoma

Abstract
A case of unilateral nearly total hypoperfusion of the left lung in a 13-mo.-old girl is presented. The combination of the lung hypoperfusion and accumulation of the Tc-99m MDP [methylene diphosphonate] and Ga-67 citrate in the same area suggested the preoperative diagnosis of mediastinal neuroblastoma. Explorative thoracotomy revealed the presence of a neuroblastoma compressing the left lung pedicle. The described scintigraphic appearance in the pediatric age group is suggested as typical of mediastinal neuroblastoma. This pathology should be included in the following gamuts in nuclear medicine: unilateral decrease or absent lung perfusion, unilateral diffuse chest uptake of Ga-67 citrate, and unilateral pulmonary uptake in bone scintigraphy.

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