The 17p-Syndrome: A Distinct Myelodysplastic Syndrome Entity?
- 1 January 1997
- journal article
- research article
- Published by Taylor & Francis in Leukemia & Lymphoma
- Vol. 25 (1-2) , 163-168
- https://doi.org/10.3109/10428199709042506
Abstract
The 17p-syndrome is a subset of myelodysplastic syndrome characterized by “typical” dysgranulopoïesis, combining a pseudo-Pelger-Hüet and a deletion of the short arm of chromosome 17. We describe two patients; one with de novo myelodysplastic syndrome (RAEB), one with secondary MDS (RAEB-T). Both showed a 17p-deletion resulting from tanslocations involving 17p associated with an additional complex cytogenetics, and both of them had a particular type of dysgranulopoïesis, combining pseudo-Pelger-Hüet anomaly.Keywords
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