Pulmonary Ventilation During Exercise and Inhalation of Carbon Dioxide

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Abstract
Respiratory minute volumes (V) of 3 men were followed during inhalation of CO2 mixtures up to 8% (C) and standing, walking or running on a level treadmill at speeds up to 6 mph (M). The conditions were studied in combination up to 6% CO2 and 4 mph. The results were fitted by the equation Log V = d + eC + dM-gCM with an average deviation of 2 l/min. In this system the lines representing constant CO2 concentration or treadmill speed converge and when extrapolated come to a point. It is concluded that while the minute volume was multiplied by factors for CO2 and treadmill speed, each factor operated so as to diminish the action of the other.