One Hundred and Twenty-Seven Cultured Human Tumor Cell Lines Producing Tumors in Nude Mice23

1 July 1977

journal article
research article
Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute

Vol. 59 (1) , 221-226
https://doi.org/10.1093/jnci/59.1.221

Abstract

One hundred and twenty-seven cultured human tumor cell lines produced tumors after sc inoculation of 1–20 million cells into nude mice. They included 56 carcinoma lines, 14 sarcoma lines, and 57 lines from miscellaneous tumors and were all glucose-6-phosphate dehydrogenase type B. Twenty-nine percent of the lines produced tumors of 1 cm³ size within 1 month and 41% in the second month after inoculation. The histopathology correlated with the human tumor of origin in all cases.

Keywords

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