Focal Adhesion Kinase Is Required for Blood Vessel Morphogenesis
- 21 February 2003
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 92 (3) , 300-307
- https://doi.org/10.1161/01.res.0000055016.36679.23
Abstract
The nonreceptor tyrosine kinase focal adhesion kinase (FAK) is a point of convergence for signals from extracellular matrix, soluble factors, and mechanical stimuli. Targeted disruption of the fak ...Keywords
This publication has 37 references indexed in Scilit:
- A fibronectin fragment inhibits tumor growth, angiogenesis, and metastasisProceedings of the National Academy of Sciences, 2001
- Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1Nature Medicine, 2000
- Thrombospondin-2: A potent endogenous inhibitor of tumor growth and angiogenesisProceedings of the National Academy of Sciences, 1999
- Focal Adhesion Kinase Mediates the Integrin Signaling Requirement for Growth Factor Activation of Map KinaseThe Journal of cell biology, 1999
- Effects of Angiogenesis Inhibitors on Multistage Carcinogenesis in MiceScience, 1999
- Signaling through focal adhesion kinaseProgress in Biophysics and Molecular Biology, 1999
- Mechanisms of angiogenesisNature, 1997
- Endostatin: An Endogenous Inhibitor of Angiogenesis and Tumor GrowthCell, 1997
- Mesodermal development in mouse embryos mutant for fibronectinDevelopmental Dynamics, 1996
- Failure of blood-island formation and vasculogenesis in Flk-1-deficient miceNature, 1995