Allergic Blepharoconjunctivitis Due to Phenylephrine

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Abstract
Acute allergic blepharoconjunctivitis with mucopurulent discharge due to phenylephrine eye drops is reported. The reaction begins 3-4 hours after drug application,persists for 12 hours and regresses gradually within 72 hours.This clinical picture occurs with a phenylephrine concentration as low as 0.1%.Conjunctival biopsy of the inflamed eyes reveals marked infiltration by lymphocytes, plasma cells and eosinophiles, without predominance of any of these cells.

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