Theophylline pharmacokinetics after intravenous infusion with ethylenediamine or sodium glycinate.
- 31 August 1986
- journal article
- research article
- Published by Wiley in British Journal of Clinical Pharmacology
- Vol. 22 (3) , 351-355
- https://doi.org/10.1111/j.1365-2125.1986.tb02899.x
Abstract
Six healthy volunteers received two theophylline preparations by short intravenous infusion, at weekly intervals in a randomized cross‐over design. The solubilizer was ethylenediamine or sodium glycinate. Plasma concentrations of theophylline and ethylenediamine were measured by h.p.l.c. for up to 24 h after dosing. The pharmacokinetics of theophylline did not show any significant intra‐subject variation associated with the solubilizing agent used.This publication has 18 references indexed in Scilit:
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