THE NUTRITIVE DEFICIENCY OF MILK WITH SPECIFIC REFERENCE TO MANGANESE, ENERGY AND PITUITARY RELATIONS

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Abstract
The capacity of pituitary transplants to stimulate ovarian development in rats was not increased by the addition of Mn to a milk-Cu-Fe diet. Though hyper-vitaminosis D inhibits ovulation, pituitary transplants from [male] rats receiving an excessive amount of vitamin D were found equally potent with controls. Deprivation of water did not produce a profound influence on pituitary potency; small differences, however, may have escaped detection. Subnormal estrus in rats raised on a successful stock rat ration was corrected in 9 out of 10 cases by improving the diet through the inclusion of liver, egg yolk, wheat germ oil, yeast and cod liver oil. The addition of sucrose or milk solids to a milk-Cu-Fe diet improved growth, ovulation and reproduction. A deficiency of milk in energy for reproduction is therefore suggested. When energy was supplied as sucrose the growth of young was inferior. The feeding of desiccated thyroid did not increase the frequency of estrus. Estrus was promptly inhibited by change to diets low in vitamin B or protein.

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