Optical trapping of microspheres as a model for biological cells
- 13 January 2003
- conference paper
- Published by Institute of Electrical and Electronics Engineers (IEEE)
- Vol. 235, 1203-1204
- https://doi.org/10.1109/iembs.1989.96160
Abstract
An analytical model has been developed to predict, in three dimensions, the forces exerted on dielectric microspheres in an optical trap. Results for a single-beam gradient force trap predict the existence of a stable trapping location and an effective trapping range. A minimum trapping power of approximately 5 mW, and an effective axial range of approximately 9 mu m, have been measured for polystyrene microspheres suspended in water and are in reasonable agreement with theoretical results. Applications of the model to the optical trapping of biological cells and chromosomes are described.Keywords
This publication has 7 references indexed in Scilit:
- Use of a laser-induced optical force trap to study chromosome movement on the mitotic spindle.Proceedings of the National Academy of Sciences, 1989
- Optical trapping and manipulation of single cells using infrared laser beamsNature, 1987
- Optical Trapping and Manipulation of Viruses and BacteriaScience, 1987
- Observation of a single-beam gradient force optical trap for dielectric particlesOptics Letters, 1986
- La lévitation optique de sphèresCanadian Journal of Physics, 1979
- Light scattering from biological cells: dependence of backscatter radiation on membrane thickness and refractive indexApplied Optics, 1979
- Acceleration and Trapping of Particles by Radiation PressurePhysical Review Letters, 1970