Catalytic Enantioselective Alkylation of Substituted Dioxanone Enol Ethers: Ready Access to C(α)‐Tetrasubstituted Hydroxyketones, Acids, and Esters
- 20 August 2008
- journal article
- research article
- Published by Wiley in Angewandte Chemie International Edition in English
- Vol. 47 (36) , 6873-6876
- https://doi.org/10.1002/anie.200801424
Abstract
Adaptive Alkylation: Palladium‐catalyzed asymmetric alkylation enables access to fully substituted enantioenriched oxygenated stereocenters, which can be transformed easily to α‐hydroxyketones, esters, and acids, providing a catalytic, enantioselective synthesis for natural products.Keywords
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