STRUCTURE OF TRINUCLEAR TRIAMINOTRICARBOXYLIC ACID (Y) IN ACTINOIDINE

  • 1 January 1981
    • journal article
    • research article
    • Vol. 26  (11) , 816-820
Abstract
The products of triaminotricarboxylic acid (Y) transformation in alkaline and reduction (HI/P) hydrolysis and the PMR spectra of the Y-Phe dipeptide were studied and the nature of the 3 amino acid substituents and their position in the aromatic nuclei were determined. With regard to the data on the structure of the aromatic skeleton published earlier, the structure of the Y amino acid as 3-(2-chloro-4-serylphenoxy)-5-(4-serylphenoxy)-p-hydroxyphenylglycine was suggested. The presence of 2 alcoholic groups of the phenylserine fragments of the Y amino acid in the actinoidine aglycone was shown with additional acetylation (Ac2O/Py) of N-acetylmethoxyaglycone. It was found with O-acetylation of N-acetylmethoxyactinosaminyl aglycone that the actinosamine amino sugar in the actinoidine molecule was bound with one of the above groups.