Rotaxane Synthesis via Nucleophilic Substitution Reactions: The Trapping of Electrophilic Threads by Organic Anion-Wheel Complexes

Abstract
Using the recently introduced trapping method based on the reaction of nucleophilic organic anion-macrolactam complexes with electrophilic building blocks, a series of new rotaxanes was synthesized upon formation of sulfide, N-tosylamide, thioester and phosphate bonds. The yields are high (41-88%) which underlines the versatility of the new synthetic concept.

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