Die Beantwortung eines homologen Gewebsstimulus (Homotransplantation) durch das lymphoretikuläre System

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Abstract
A skin homograft affects the histologic appearance of the lymph node draining the site involved. Large cortical lymphocytic masses, also known as tertiary nodules, appear in the node as the result of blood lymphocyte migration. Also, in the cortex small lymphocytes become transformed into large pyroninophilic cells which multiply and form small and medium size lymphocytes. Immature and mature plasma cells accumulate and active germinal centers develop. It is believed that the lymphocytes derived from the pyroninophilic cells are the responsible agents for rejection of the skin homograft.