Nitric Oxide during Altitude Acclimatization
- 17 November 2011
- journal article
- letter
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 365 (20) , 1942-1944
- https://doi.org/10.1056/nejmc1107887
Abstract
Hypobaric hypoxia occurs during ascent to higher altitude. In this observational study of healthy lowland dwellers, intracellular red-cell forms of nitric oxide, S-nitrosohemoglobin, and iron nitrosyl hemoglobin increased strikingly during ascent to 5050 m.Keywords
This publication has 4 references indexed in Scilit:
- The New Chemical Biology of Nitrite Reactions with Hemoglobin: R-State Catalysis, Oxidative Denitrosylation, and Nitrite Reductase/AnhydraseAccounts of Chemical Research, 2008
- Higher blood flow and circulating NO products offset high-altitude hypoxia among TibetansProceedings of the National Academy of Sciences, 2007
- An S -nitrosothiol (SNO) synthase function of hemoglobin that utilizes nitrite as a substrateProceedings of the National Academy of Sciences, 2006
- Red Blood Cell Nitric Oxide as an Endocrine VasoregulatorCirculation, 2004