The case, which forms the subject of this paper, was under the care and treatment of Dr. John M. McCleery, American Mission, Doleib Hill, Malakal, and I am indebted to him for the material sent for histopathological examination, as well as for the photographic figures 1 and 2 and the notes on the clinical history of the case. The patient was that of a male, approximately thirty-five years of age, a native of the Southern Sudan, who came to the American Mission for treatment. This mission station is about 500 miles south of Khartoum, and obtains a number of patients from the various Nuer, Dinka and Shilluk tribes who frequent that district. On examination, the patient was found to have a large indurated ulcerated area involving the lower part of the right nipple. The ulcer had existed for a period of nearly a year and was relatively painless. There was no previous history of trauma connected with the lesion.