Hippocampal sclerosis following brief generalized seizures in adulthood
- 24 July 2001
- journal article
- case report
- Published by Wolters Kluwer Health in Neurology
- Vol. 57 (2) , 315-317
- https://doi.org/10.1212/wnl.57.2.315
Abstract
This report describes a patient who had a first generalized tonic clonic seizure (GTCS) at the age of 18 years. The initial MRI scan was normal on visual and quantitative examination. After a further six GTCS, a second MRI scan showed reduced hippocampal volume and increased hippocampal T2 signal, which was confirmed in a third scan. Therefore, hippocampal sclerosis may be acquired in adulthood after brief GTCS.Keywords
This publication has 11 references indexed in Scilit:
- Hippocampal Sclerosis: Development in Adult LifeDevelopmental Neuroscience, 1999
- Longitudinal Quantitative Hippocampal Magnetic Resonance Imaging Study of Adults with Newly Diagnosed Partial Seizures: One‐Year Follow‐Up ResultsEpilepsia, 1998
- Recurrent seizures may cause hippocambal damage in temporal lobe epilepsyNeurology, 1998
- Magnetic resonance imaging evidence of hippocampal injury after prolonged focal febrile convulsionsAnnals of Neurology, 1998
- MRS Metabolic Markers of Seizures and Seizure‐Induced Neuronal DamageEpilepsia, 1998
- Development of Hippocampal Atrophy: A Serial Magnetic Resonance Imaging Study in a Patient Who Developed Epilepsy After Generalized Status EpilepticusEpilepsia, 1997
- Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizuresProceedings of the National Academy of Sciences, 1997
- Detection of hippocampal pathology in intractable partial epilepsyNeurology, 1993
- Etiology and Pathogenesis of Temporal Lobe EpilepsyArchives of Neurology, 1964