Abstract
Occupationally acquired infections are a significant hazard among laboratory workers. Frequency rates found range from 0.1 to 50.0 infections per million man-hours. Unsafe acts or conditions are difficult to identify in approximately 80% of the cases. The sources and causes of such infections are discussed and criteria given for assessment of risk. Five specific approaches to controlling microbiological hazards are: (1) management support and administrative techniques, (2) vaccination of personnel, (3) use of correct laboratory techniques, (4) use of safety equipment, and (5) proper design of laboratories.

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