Hepatitis C viremia persistently suppressed by HAART.

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Abstract
Sir—We read with great interest the review by Cooper et al. [1] on the effect of highly active antiretroviral therapy (HAART) on hepatitis C virus (HCV) RNA in human immunodeficiency virus (HIV) and HCV coinfection. The authors found that the initiation of HIV treatment might cause an initial increase of HCV RNA levels (accompanied or not by elevated transaminase levels) followed by a decrease to levels lower than those before treatment. This response might be due to the so-called “immunorestoration syndrome.” Our data agree with those of Puoti et al. [2], but we would like to report a singular case of complete and persistent suppression of HCV RNA levels and normalization of serum transaminase levels in a patient coinfected with HIV and HCV who was receiving HAART.