Comparative Evaluation of99mTc GH,99mTcO4, and99mTc DTPA as Brain Imaging Agents

Abstract
The brain imaging properties of 99mTc glucoheptonate [99mTc GH], 99mTc pertechnetate and 99mTc diethylenetriaminepentaacetate [99mTc DTPA] were compared [in humans]. Optimum images are obtained at 90, 180 and 180 min, for 99mTc GH, 99mTc DTPA and 99mTc pertechnetate, respectively. The former 2 images were not affected by prior bone imaging with 99mTc pyrophosphate, while 99mTc pertechnetate images were adversely affected. 99mTc glucoheptonate was the superior agent for brain imaging, followed by 99mTc DTPA and 99mTc pertechnetate.

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