Transferrin: Internal Homology in the Amino Acid Sequence
- 26 December 1975
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 190 (4221) , 1306-1307
- https://doi.org/10.1126/science.1198114
Abstract
Two regions of the primary structure of human serum transferrin, of 87 and 57 residues, are reported. When these are suitably aligned by placing two gaps, 40 percent of the amino acids in corresponding positions are identical. This indicates that the doubling of an ancestral structural gene occurred during the evolution of the transferrins.Keywords
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