Observations of the concentration of zinc and iron in tissues of vitamin B6-deficient germ-free rats.
- 1 January 1979
- journal article
- research article
- Published by Center for Academic Publications Japan in Journal of Nutritional Science and Vitaminology
- Vol. 25 (3) , 151-158
- https://doi.org/10.3177/jnsv.25.151
Abstract
The transition of Zn and Fe metabolism in vitamin B6 deficiency was investigated using germ-free and conventional rats. In contrast to previous reports a decrease in Zn content was not observed in the liver, pancreas, kidney, spleen, lung or testes of vitamin B6-deficient conventional and germ-free rats, but an increase in Zn content in the kidney of conventional rats and in the liver and spleen of germ-free fats was found. Vitamin B6-deficient conventional and germ-free rats retained more Fe in their tissues than the control animals except for the spleen of germ-free rats. The deposit of Fe was more evident in vitamin B6-deficient germ-free rats than in vitamin B6-deficient conventional rats, and is possibly proportional to the degree of vitamin B6 deficiency. The deposit of Fe in the organs apparently had some influence on metabolic disorders in vitamin B6-deficient rats.This publication has 0 references indexed in Scilit: