Physiological Mechanisms of Tumor-Cell Invasion and Migration
- 1 June 2005
- journal article
- review article
- Published by American Physiological Society in Physiology
- Vol. 20 (3) , 194-200
- https://doi.org/10.1152/physiol.00009.2005
Abstract
Recent advances in understanding the complex biology of the microenvironment that underlies tumor invasion and migration have revealed novel and promising therapeutic targets. Pharmacological blockade of intra- and extracellular signaling events that regulate migration and survival of multiple cell types may disrupt the host-tumor conspiracy that allows escape from normal developmental regulation.Keywords
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