The location of the polio genome protein in viral RNAs and its implication for RNA synthesis
- 1 July 1977
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 268 (5617) , 208-213
- https://doi.org/10.1038/268208a0
Abstract
Evidence is presented that a small protein (VPg) is covalently attached to the 5''-terminal oligonucleotide VPg-pU-U-A-A-A-A-C-A-Gp of the polio genome, to nascent strands of the polio replicative intermediate and to poly(U) of minus strands. A model of polio RNA replication is proposed implicating VPg in initiation of RNA synthesis, possibly as primer.This publication has 22 references indexed in Scilit:
- A protein covalently linked to poliovirus genome RNA.Proceedings of the National Academy of Sciences, 1977
- The Genome of Poliovirus Is an Exceptional Eukaryotic mRNAProgress in Nucleic Acid Research and Molecular Biology, 1977
- Capping of eucaryotic mRNAsCell, 1976
- Absence of 5' terminal capping in encephalomyocarditis virus RNANucleic Acids Research, 1976
- The 5' end of poliovirus mRNA is not capped with m7G(5')ppp(5')Np.Proceedings of the National Academy of Sciences, 1976
- 5'-terminal structure of poliovirus polyribosomal RNA is pUp.Proceedings of the National Academy of Sciences, 1976
- Substrate Specificity of Nuclease P1Agricultural and Biological Chemistry, 1974
- Sequence studies of poliovirus RNAJournal of Molecular Biology, 1972
- Sequence studies of satellite tobacco necrosis virus RNA: Isolation and characterization of a 5′-terminal trinucleotideJournal of Molecular Biology, 1968
- A Proposed General Procedure for Isolating End-Groups of Nucleic Acids*Biochemistry, 1963