STRUCTURAL BIOCHEMISTRY 17. Synthesis of Tryptophan Dipeptides*

Abstract
Boc‐Trp‐Leu hydrazide has been found to significantly inhibit growth of the L‐1210 and P388 murine lymphocytic leukemias. A series of related tryptophan dipeptides were prepared and found to be devoid of such activity. The tryptophan dipeptides were most conveniently obtained employing the DCCI‐NHS peptide bond‐forming procedure.