High resolution multicolor-banding: a new technique for refined FISH analysis of human chromosomes
- 14 June 1999
- journal article
- research article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 84 (3-4) , 156-160
- https://doi.org/10.1159/000015245
Abstract
A new multicolor-banding technique has been developed which allows the differentiation of chromosome region specific areas at the band level. This technique is based on the use of differently labeled overlapping microdissection libraries. The changing fluorescence intensity ratios along the chromosomes are used to assign different pseudo-colors to specific chromosome regions. The multicolor banding of human chromosome 5 is presented as an example.Keywords
This publication has 8 references indexed in Scilit:
- Cross‐species colour segmenting: A novel tool in human karyotype analysisCytometry, 1998
- An optimized, fully automated system for fast and accurate identification of chromosomal rearrangements by multiplex-FISH (M-FISH)Cytogenetic and Genome Research, 1998
- Hidden chromosome abnormalities in haematological malignancies detected by multicolour spectral karyotypingNature Genetics, 1997
- PRENATAL DIAGNOSIS OF A HALF-CRYPTIC TRANSLOCATION USING CHROMOSOME MICRODISSECTIONPrenatal Diagnosis, 1997
- Refinement of the locus for autosomal dominant cerebellar ataxia type II to chromosome 3p21.1-14.1Human Genetics, 1997
- Treaty Draft Raises Scientific HacklesScience, 1996
- Karyotyping human chromosomes by combinatorial multi-fluor FISHNature Genetics, 1996
- A diacylglycerol analogue reduces neuronal calcium currents independently of protein kinase C activationNature, 1989