Replacement Time for Alveolar Lipid Removed by Pulmonary Lavage: Effects of Mutliple Lavage on Lung Lipids
- 1 January 1975
- journal article
- research article
- Published by Taylor & Francis in Archives of Physiology and Biochemistry
- Vol. 83 (2) , 261-269
- https://doi.org/10.3109/13813457509081870
Abstract
Daily washing in vivo of the lung with 0.15 M saline did not deplete the Beagle dog lung of surfactant lipids, but rather increased the quantity of surfactant lipid in the tissue. Replacement time for the lung lipids removed by the lavage was approximately 5 hours. This rate is one indication of the time required for movement of surfactant lipid from storage areas to the surface of the alveoli. The increase in tissue surfactant lipid following multiple lavage suggests that the rate of surfactant lipid synthesis is controlled in part by the level of surfactant lipid in the alveoli.Keywords
This publication has 6 references indexed in Scilit:
- Removal of 144Ce in Fused Clay Particles from the Beagle Dog Lung by Bronchopulmonary LavageHealth Physics, 1974
- Influence of Sex and Age on the Pulmonary Function of the Unanesthetized Beagle DogJournal of Gerontology, 1974
- Protein Transport by LungExperimental Biology and Medicine, 1974
- Methods for Determining the Fraction of Pulmonary Surfactant Lipid Removed from the Lung of Beagle Dogs by LavageArchives Internationales de Physiologie et de Biochimie, 1974
- Beagle dog pulmonary surfactant lipids. Lipid composition of pulmonary tissue, exfoliated lining cells and surfactantArchives of internal medicine (1960), 1971
- The Biochemical Development of Surface Activity in Mammalian Lung: I. The Surface-Active Phospholipids; the Separation and Distribution of Surface-Active Lecithin in the Lung of the Developing Rabbit FetusPediatric Research, 1967