Gilbert's Syndrome — A Legitimate Genetic Anomaly?
- 2 November 1995
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 333 (18) , 1217-1218
- https://doi.org/10.1056/nejm199511023331812
Abstract
Gilbert's syndrome consists of chronic, mild, unconjugated hyperbilirubinemia in the absence of overt hemolysis or evidence of structural or functional liver disease.13 The elevated serum bilirubin concentration is usually noted first in adolescence, either as an incidental finding or because of a slight yellow discoloration of the sclerae. The serum bilirubin concentration characteristically fluctuates daily, occasionally falling within the normal range but at other times, especially during fasting, physical exercise, stress, intercurrent illness, or menstruation, exceeding the upper limit of normal, sometimes by as much as three to four times. The way in which the diagnostic level is selected . . .Keywords
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