Chromosomal localization of a human myosin heavy-chain gene by in situ hybridization
- 1 December 1983
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 65 (2) , 195-197
- https://doi.org/10.1007/bf00286663
Abstract
A cloned rabbit heart muscle myosin heavy-chain cDNA was hybridized in situ with human metaphase chromosomes. The probe was known to have sequence homology with human genomic heavy-chain DNA. Only one site in the human haploid karyotype was labeled with the cDNA, and this site was found on the short arm of chromosome 17. The localization of autoradiographic grains suggests a subregional assignment of the myosin heavy-chain locus to 17p 1,2-pter.This publication has 20 references indexed in Scilit:
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