Results of Inferior Vena Cava Resection for Renal Cell Carcinoma

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Abstract
A total of 24 patients with renal cell carcinoma involving the inferior vena cava underwent thoracoabdominal radical nephrectomy with removal of tumor thrombus by an open or closed technique. The tumor extended in the inferior vena cava to the level of the renal or lower hepatic veins in 18 patients, and it reached the level of the diaphragm or right atrium in 6. Of the 24 patients, 3 with preoperative findings minimally suggestive of disseminated disease were shown later to have metastases in the questionable areas, 3 with disease at the level of the diaphragm had incomplete resections, 4 had metastases to regional lymph nodes and 1 had questionable preoperative findings and lymph node metastases. Only 13 of the 24 patients (54%) did not have disseminated or residual tumor postoperatively. The mean survival duration of this subgroup (20 mo.) was comparable to that of the group as a whole (21 mo.). Four patients for this subgroup are free of disease, with a mean follow-up of 30 mo. There was 1 postoperative death. Morbidity, including renal failure, intraoperative hypotension and sepsis, was common. The prognosis for patients with renal cell carcinoma and inferior vena caval involvement apparently is guarded.