Regional mapping of the gene for human UDPGal 4-epimerase on chromosome 1 in mouse-human hybrids
- 1 January 1979
- journal article
- research article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 24 (4) , 217-223
- https://doi.org/10.1159/000131383
Abstract
Somatic cell hybrids between mouse and human cells containing two different reciprocal translocations involving human chromosome 1, 46, X, t(l;X)(ql2;q26) and 47, XX, + 21, t(l;17)(p32;pl3), were studied for the expression of human uridine diphosphate galactose 4-epimerase (UDPGal 4-epimerase, E.C. 5.1.3.2) by starch-gel electrophoresis. Analysis of the hybrid clones for the expression of the enzyme and the presence of the translocation chromosome 1 has permitted the assignment of the gene for human UDPGal 4-epimerase to the pter→p32 region of chromosome 1.Keywords
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