Untranslated mRNA for a chorion protein of Drosophila melanogaster accumulates transiently at the onset of specific gene amplification.
- 1 October 1980
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 77 (10) , 5789-5793
- https://doi.org/10.1073/pnas.77.10.5789
Abstract
In the cytoplasm of follicular cells of female fruitflies, a messenger RNA for one of the chorion proteins accumulates prematurely (i.e, before in vivo synthesis of the protein) but is not associated with polysomes. Subsequently, this mRNA is rapidly degraded and, thus, is not stored for later use. At a later stage in choriogenesis, the same mRNA reappears, accumulates, associates with polysomes, and is translated into a chorion protein. The transient, premature accumulation of the mRNA occurs in concert with the onset of amplification of its specific gene, a finding suggestive of a functional coupling between the two events.This publication has 20 references indexed in Scilit:
- Two clusters of genes for major chorion proteins of Drosophila melanogasterCell, 1980
- Identification of chorion protein precursors and the mRNAs that encode them in Drosophila melanogaster.Proceedings of the National Academy of Sciences, 1979
- Identification and time of synthesis of chorion proteins in Drosophila melanogasterCell, 1979
- Transcription of structural and intervening sequences in the ovalbumin gene and identification of potential ovalbumin mRNA precursorsCell, 1978
- The 5S genes of drosophila melanogasterCell, 1977
- Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.Proceedings of the National Academy of Sciences, 1977
- Specific protein synthesis in cellular differentiation: III. The eggshell proteins of Drosophila melanogaster and their program of synthesisDevelopmental Biology, 1976
- Methylmercury as a reversible denaturing agent for agarose gel electrophoresisAnalytical Biochemistry, 1976
- Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresisBiochemistry, 1975
- Quantitative measurements of fibroin messenger RNA synthesis in the posterior silk gland of normal and mutant Bombyx moriJournal of Molecular Biology, 1974