Pharmacokinetic Monitoring of Heparin Therapy for Regular Hemodialysis

1 February 1985

journal article
Published by Wiley in Artificial Organs

Vol. 9 (1) , 59-61
https://doi.org/10.1111/j.1525-1594.1985.tb04348.x

Abstract

Using a pharmacokinetic model for heparin prescription during hemodialysis leads to a precise monitoring of the coagulation time (CT) with 25% less heparin required. Two different populations were distinguished: The first group maintained stable sensitivity and elimination constant, permitting a stable prescription and giving stable CT values for up to 2 years. The other group exhibited wide variations of these parameters, necessitating daily dose monitoring.

Keywords

This publication has 3 references indexed in Scilit:

PRECISE CONTROL OF MINIMAL HEPARINIZATION FOR HIGH BLEEDING RISK HEMODIALYSIS
Asaio Journal, 1977
Management of Heparin Therapy
New England Journal of Medicine, 1975
THE KINETICS OF HEPARIN*
Annals of the New York Academy of Sciences, 1971