Colostomy irrigation with prostaglandin E2 and bisacodyl. A double-blind cross-over study
- 1 July 1984
- journal article
- clinical trial
- Published by Oxford University Press (OUP) in British Journal of Surgery
- Vol. 71 (7) , 556-557
- https://doi.org/10.1002/bjs.1800710728
Abstract
The emptying of the colon and the side‐effects after intraluminal application of prostaglandin E2 and of bisacodyl in 14 patients was studied by employing colostomy irrigation. The design was double‐blind with cross‐over. the irrigation was one litre of tap water to which was added in randomized sequence placebo, prostaglandin *2 (350, 700 and 1400 μg) or bisacodyl (1.25, 2.5 and 5 mg). Neither prostaglandin E2 nor bisacodyl had any significant effect.Keywords
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