An evaporation-based microfluidic sample concentration method
- 30 April 2002
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Lab on a Chip
- Vol. 2 (2) , 57-61
- https://doi.org/10.1039/b202473j
Abstract
We present a method for sample concentration within microfluidic devices using evaporation-induced flow. Evaporation-induced flow is easy to incorporate into microfluidic designs and can be used to concentrate a wide variety of molecules. The practicality of this method was demonstrated with 0.2 μm fluorescent spheres and FITC-labeled BSA. Thirty two percent of the 0.6 μL fluorescent sphere suspension was concentrated into a well within a microfluidic device. In the same amount of time, 93% of the 0.6 μL FITC-labeled BSA solution was concentrated.Keywords
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