Structure of the Arabidopsis RPM1 Gene Enabling Dual Specificity Disease Resistance

11 August 1995

journal article
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 269 (5225) , 843-846
https://doi.org/10.1126/science.7638602

Abstract

Plants can recognize pathogens through the action of disease resistance (R) genes, which confer resistance to pathogens expressing unique corresponding avirulence (avr) genes. The molecular basis of this gene-for-gene specificity is unknown. The Arabidopsis thaliana RPM1 gene enables dual specificity to pathogens expressing either of two unrelated Pseudomonas syringae avr genes. Despite this function, RPM1 encodes a protein sharing molecular features with recently described single-specificity R genes. Surprisingly, RPM1 is lacking from naturally occurring, disease-susceptible Arabidopsis accessions.

Keywords

This publication has 32 references indexed in Scilit:

Pièce de Résistance: Novel Classes of Plant Disease Resistance Genes
Cell, 1995
RPS2 of Arabidopsis thaliana : a Leucine-Rich Repeat Class of Plant Disease Resistance Genes
Science, 1994
The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats
Cell, 1994
Analysis of clones carrying repeated DNA sequences in two YAC libraries of Arabidopsis thaliana DNA
The Plant Journal, 1994
Functional homologs of the Arabidopsis RPM1 disease resistance gene in bean and pea.
Plant Cell, 1992
The major histocompatibility complex à la carte: are there analogies to plant disease resistance genes on the menu?
The Plant Journal, 1992
Identification of Pseudomonas syringae pathogens of Arabidopsis and a bacterial locus determining avirulence on both Arabidopsis and soybean.
Plant Cell, 1991
The P-loop — a common motif in ATP- and GTP-binding proteins
Trends in Biochemical Sciences, 1990
PFGE and YAC analysis of the Arabidopsis genome
Methods, 1990
Current Status of the Gene-For-Gene Concept
Annual Review of Phytopathology, 1971