Digitalis Poisoning and Its Treatment

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Abstract
Because digitalis preparations, acetylcholine or vagal stimulation may cause identical electrocardiographic changes in normal persons,113 early efforts were directed toward vagal paralysis with atropine. In fact, some experimental data purported to show that atropine might aid in modifying the myocardial lesions produced by digitalis.69 Clinical results were conflicting. Resnik observed a reversion to regular sinus rhythm from digitalis-induced auricular fibrillation within sixty-eight minutes after a hypodermic injection of 2 mg. of atropine75; Gold and Otto described similar success in interrupting 5 cases of digitalis bigeminy.43 On the other hand, Robinson and Wilson could not modify the toxic effects of . . .