Thermal optimisation of the Reimer–Tiemann reaction using thermochromic liquid crystals on a microfluidic reactor
- 22 March 2005
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Lab on a Chip
- Vol. 5 (5) , 540-544
- https://doi.org/10.1039/b419081e
Abstract
Microreactors incorporating thin film resistive heating elements for continuous flow organic synthesis are presented. Internal thermal conditions were monitored in real time using reflectance spectra of temperature sensitive thermochromic liquid crystals (TLC) in a collateral microfluidic network. To demonstrate the precise temperature control provided by this method, the thermal optimisation of the Reimer–Tiemann formylation of β-naphthol was performed under hydrodynamic pumping regimes.Keywords
This publication has 17 references indexed in Scilit:
- Microfabricated cross-flow chemical reactor for catalyst testingSensors and Actuators B: Chemical, 2002
- A Hantzsch synthesis of 2-aminothiazoles performed in a heated microreactor systemLab on a Chip, 2002
- FOCUSLab on a Chip, 2002
- Miniaturized flow-through PCR with different template types in a silicon chip thermocyclerLab on a Chip, 2001
- The intensification of rapid reactions in multiphase systems using slug flow in capillariesLab on a Chip, 2001
- Experimental and theoretical investigation of H2 oxidation in a high-temperature catalytic microreactorChemical Engineering Science, 2001
- Microreaction engineering — is small better?Chemical Engineering Science, 2001
- Simulation of micromachined chemical reactors for heterogeneous partial oxidation reactionsChemical Engineering Science, 2000
- Micromachined heated chemical reactor for pre-column derivatisationJournal of Chromatography A, 1998
- Transient liquid crystal thermometry of microfabricated PCR vessel arraysJournal of Microelectromechanical Systems, 1998