Tiaprofenic acid induced photosensitivity
- 11 April 1989
- journal article
- research article
- Published by Wiley in Contact Dermatitis
- Vol. 20 (4) , 270-273
- https://doi.org/10.1111/j.1600-0536.1989.tb03144.x
Abstract
45 patients (34 patients with PLE, 11 with phototoxic or photoallergic dermatitis) were photopatch tested to tiaprofenic acid. In 23 patients (51%), phototoxic reactions were found. Positive reactions appeared within 0.5 to 48 h of irradiation. Although each patient was irradiated with 2 different UVA light sources, with significantly different energy outputs (10 J/cm2 against 72 J/cm2), the intensity and duration of positive reactions was virtually the same. We found a considerably higher rate of positive reactions than other investigators, independent of the light energy delivered. None of the patients gave a history of previous tiaprofenic acid exposure.Keywords
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