Walks of molecular motors in two and three dimensions
- 1 May 2002
- journal article
- Published by IOP Publishing in Europhysics Letters
- Vol. 58 (3) , 468-474
- https://doi.org/10.1209/epl/i2002-00662-4
Abstract
Molecular motors interacting with cytoskeletal filaments undergo peculiar random walks consisting of alternating sequences of directed movements along the filaments and diffusive motion in the surrounding solution. An ensemble of motors is studied which interacts with a single filament in two and three dimensions. The time evolution of the probability distribution for the bound and unbound motors is determined analytically. The diffusion of the motors is strongly enhanced parallel to the filament. The analytical expressions are in excellent agreement with the results of Monte Carlo simulations.Keywords
All Related Versions
This publication has 6 references indexed in Scilit:
- Random Walks of Cytoskeletal Motors in Open and Closed CompartmentsPhysical Review Letters, 2001
- Universal Aspects of the Chemomechanical Coupling for Molecular MotorsPhysical Review Letters, 2000
- Direct Observation of One-Dimensional Diffusion and Transcription by Escherichia coli RNA PolymeraseBiophysical Journal, 1999
- Guidebook to the Cytoskeletal and Motor ProteinsPublished by Oxford University Press (OUP) ,1999
- Transport by Active FilamentsEurophysics Letters, 1995
- One-dimensional diffusion of microtubules bound to flagellar dyneinCell, 1989