The Role of Hyperglycemia in Acute Stroke

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Abstract
DIABETES MELLITUS is associated with increased risk of stroke and coronary heart disease and remains an independent risk factor for both after adjusting for other known risk factors.1-3 Many studies have shown that patients with diabetes have a less favorable course than those without following myocardial infarction (MI).4,5 Furthermore, stress hyperglycemia in patients without diabetes was found to be associated with increased in-hospital mortality after MI.6 The Diabetes and Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) Study has recently provided compelling evidence that achieving euglycemia during acute MI resulted in a significant reduction of long-term mortality.7 These results have revolutionized the standard care of patients with diabetes and acute MI.