Amelioration of myoglobinuric renal damage in rats by chronic exposure to flavonol-rich red wine

Abstract
Background. Myoglobinuric acute renal failure causes increased oxidative stress. Since ethanol upregulates renal antioxidant enzymes and wine polyphenols behave as antioxidants, we tested the hypothesis that red wine components would ameliorate the renal damage caused by rhabdomyolysis.